Evaluation of the Oral Antimitotic Agent (ABT-751) in Dogs with Lymphoma

Author:

Silver M.1,Rusk A.1,Phillips B.2,Beck E.3,Jankowski M.4,Philibert J.5,Hahn K.6,Hershey E.7,McKeegan E.8,Bauch J.8,Krivoshik A.8,Khanna C.1

Affiliation:

1. Animal Clinical Investigation; LLC and The Oncology Service; Washington; DC

2. Veterinary Specialty Hospital; San Diego; CA

3. Regional Veterinary Referral Center; Springfield; VA

4. Southpaws Veterinary Referral Center; Fairfax; VA

5. New England Veterinary Oncology Group; Waltham; MA

6. Hill's Pet Nutrition, Inc; Topeka; KS

7. Arizona Veterinary Specialists; Gilbert; AZ

8. Abbott Laboratories

Publisher

Wiley

Subject

General Veterinary

Reference14 articles.

1. Mechanism of action of E7010, an orally active sulfonamide antitumor agent: Inhibition of mitosis by binding to the colchicine site of tubulin;Yoshimatsu;Cancer Res,1997

2. In vivo tumor growth inhibition produced by a novel sulfonamide, E7010, against rodent and human tumors;Koyanagi;Cancer Res,1994

3. The pharmacokinetics and safety of ABT-751, a novel, orally bioavailable sulfonamide antimiotic agent: Results of a phase I study;Hande;Clin Cancer Res,2006

4. Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations;Jordan;Cell Biol,1993

5. STX140 is efficacious in vitro and in vivo in taxane-resistant breast carcinoma cells;Newman;Clin Cancer Res,2008

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