Topical combination of meldonium and N‐acetyl cysteine relieves allodynia in rat models of CRPS‐1 and peripheral neuropathic pain by enhancing NO‐mediated tissue oxygenation
Author:
Affiliation:
1. Department of Anesthesia McGill University Montreal QC Canada
2. Department of Chemistry McGill University Montreal QC Canada
Funder
Canadian Institutes of Health Research
Health Research
Natural Sciences and Engineering Research Council of Canada
Publisher
Wiley
Subject
Cellular and Molecular Neuroscience,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/jnc.14943
Reference54 articles.
1. Efficacy of Opioids for Chronic Pain
2. N ‐acetylcysteine (NAC) in neurological disorders: mechanisms of action and therapeutic opportunities
3. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man
4. Antioxidants and vascular health
5. Experimental tissue acidosis leads to increased pain in complex regional pain syndrome (CRPS)
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