Randomized Controlled Trials and Challenge Trials: Design and Criterion for Validity

Author:

Sargeant J. M.12,Kelton D. F.12,O'Connor A. M.3

Affiliation:

1. Centre for Public Health and Zoonoses; University of Guelph; Guelph ON Canada

2. Department of Population Medicine; Ontario Veterinary College; University of Guelph; Guelph ON Canada

3. Department of Veterinary Diagnostic and Production Animal Medicine; Iowa State University College of Veterinary Medicine; Ames IA USA

Publisher

Wiley

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Veterinary,General Immunology and Microbiology,Epidemiology

Reference45 articles.

1. Statistics and ethics in medical research: III How large a sample?;Altman;BMJ,1980

2. Comparability of Randomised Groups;Altman;J. R. Stat. Soc. Series D. (The Statist.),1985

3. Randomisation: essential for reducing bias;Altman;BMJ,1991

4. Absence of evidence is not evidence of absence;Altman;BMJ,1995

5. Suspended judgment. Significance tests of covariate imbalance in clinical trials;Begg;Control. Clin. Trials,1990

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