Pharmacokinetics of furosemide administered 4 and 24 hours prior to high-speed exercise in horses

Author:

Knych H. K.12ORCID,Vale A.3,Wilson W. D.4,Kass P. H.5,Arthur R. M.6,Jones J. H.7

Affiliation:

1. K.L. Maddy Equine Analytical Chemistry Laboratory; School of Veterinary Medicine; University of California; Davis CA USA

2. Department of Veterinary Molecular Biosciences; School of Veterinary Medicine; University of California; Davis CA USA

3. Private Practitioner; San Diego CA USA

4. Department of Medicine and Epidemiology; School of Veterinary Medicine; University of California; Davis CA USA

5. Department of Population Health and Reproduction; School of Veterinary Medicine; University of California; Davis CA USA

6. School of Veterinary Medicine; University of California; Davis CA USA

7. Department of Surgical & Radiological Sciences; School of Veterinary Medicine; Davis CA USA

Funder

Grayson-Jockey Club Research Foundation

American Association of Equine Practitioners Foundation

Churchill Downs

Del Mar Thoroughbred Club

Keeneland Foundation

Kentucky Downs

The Stronach Group

New York Racing Association

Oak Tree Racing Association

Oaklawn Park

The Thoroughbred Horseman's Association

Publisher

Wiley

Subject

General Veterinary,Pharmacology

Reference11 articles.

1. The pharmacology of furosemide in the horse: V. Pharmacokinetics and blood levels of furosemide after intravenous administration;Chay;Drug Metabolism and Disposition,1983

2. Detection, quantification, and pharmacokinetics of furosemide and its effects on urinary specific following IV administration to horses;Dirikolu;Veterinary Therapeutics,2003

3. The effects of submaximal exercise on the pharmacokinetics of furosemide in horses;Dyke;Journal of Veterinary Pharmacology and Therapeutics,1996

4. Exercise-induced alterations in hepatic function in mares;Dyke;Journal of Applied Physiology,1985

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