Comparative analysis of milk fat globule membrane proteins between porcine and human colostrum by a label‐free proteomics approach

Author:

Zhao Huiwen1ORCID,Zhang Zhenghan1,Liu Xianjun2,Li Jiantao2,Song Wanying1,Yue Xiqing1ORCID,Liu Xiaoyu3

Affiliation:

1. College of Food Science, Shenyang Agricultural University Shenyang 110866 China

2. College of Animal Science and Veterinary Medicine, Shenyang Agricultural University Shenyang 110866 China

3. Department of Obstetrics and Gynaecology General Hospital of Northern Theater Command Shenyang 110016 China

Abstract

This study aimed to investigate the similarities and differences in milk fat globule membrane (MFGM) proteins from porcine colostrum (PC) and human colostrum (HC) based on a label‐free proteomics approach. In total, 3901 and 4027 MFGM proteins were identified in PC and HC, respectively, including 3452 common proteins. Similar biological functions and pathways were found in two groups, whereas the quantities and types of MFGM proteins involved were different. This study compared the differences between MFGM proteins in PC and HC, effectively expanding the MFGM proteome and its bioinformatic database and providing new insights for the exploration of porcine milk.

Funder

Distinguished Professor of Liaoning Province

Publisher

Wiley

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