Antihypertensive effects of the <i>Limosilactobacillus reuteri</i> Z09 and <i>Lactobacillus helveticus</i> Z11 fermented milk in spontaneously hypertensive rats-Reference-Cited by-同舟云学术

Antihypertensive effects of the Limosilactobacillus reuteri Z09 and Lactobacillus helveticus Z11 fermented milk in spontaneously hypertensive rats

Published:2024-06-18 Issue: Volume: Page:
ISSN:1364-727X
Container-title:International Journal of Dairy Technology
language:en
Short-container-title:Int J of Dairy Tech

Author:

Song Xiaoling¹,Fu Jinfeng¹^ORCID,Ding Qinchao¹²,Cao Feiwei¹²,Zhang Xiu³,Zhang Yanan¹,Lai Shanglei⁴,Zhug Hui⁴,Valencak Teresa G¹,Ren Daxi¹⁵^ORCID

Affiliation:

1. College of Animal Sciences, Institute of Dairy Science Zhejiang University Hangzhou 310058 China

2. School of Public Health Zhejiang Chinese Medical University Hangzhou 310053 China

3. Ningxia Key Laboratory for the Development and Application of Microbial Resources in Extreme Environments, College of Biological Science and Engineering North Minzu University Yinchuan 750021 China

4. School of Life Science Zhejiang Chinese Medical University Hangzhou 310053 China

5. College of Animal Sciences Xinjiang Agricultural University Urumqi 830052 China

Abstract

Recent studies have shown that lactic acid bacteria (LAB) fermentation has great potential to relieve hypertension. In this study, we verified the antihypertensive effects of Limosilactobacillus reuteri Z09, Lactobacillus helveticus Z11 and their mixed fermented milk (MIX‐FM) on spontaneously hypertensive rats (SHRs). Four weeks of administration showed that all three LAB fermentations had an antihypertensive effect on SHRs, while MIX‐FM showed the best effect. MIX‐FM had the highest angiotensin‐converting enzyme inhibitor peptide contents, and it can improve intestinal dysbiosis better than the other two groups. The above results suggest that these two strains have the potential to develop antihypertensive dairy products.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/1471-0307.13110

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