Synthesis, Anti-MRSA, and Anti-VRE Activity of Hemin Conjugates with Amino Acids and Branched Peptides

Author:

Okorochenkov Sergei A.1,Zheltukhina Galina A.1,Mirchink Elena P.2,Isakova Elena B.2,Feofanov Alexey V.3,Nebolsin Vladimir E.4

Affiliation:

1. Department of Biotechnology and Organic synthesis; Moscow State University of Fine Chemical Technology; Vernadskogo prosp., 86 119571 Moscow Russia

2. Gause Institute of New Antibiotics; Russian Academy of Medical Sciences; Bolshaya Pirogovskaya st, 11 119021 Moscow Russia

3. M.M. Shemyakin and Yu.A. Ovchinnikov Institute of bioorganic chemistry; Miklukho-Maklaya st, 16/10, GSP-7 117997 Moscow Russia

4. LTD “Pharmenterprises”; Vernadskogo prosp., 86 119571 Moscow Russia

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Reference11 articles.

1. Evolution of bacterial resistance to antibiotics during the last three decades;Gómez-Lus;Int Microbiol,1998

2. Antibiotic side effects;Cunha;Med Clin North Am,2001

3. Photodynamic therapy for methicillin-resistant Staphylococcus aureus infection in a mouse skin abrasion model;Dai;Lasers Surg Med,2010

4. Characterization of hemin antibacterial action on Staphylococcus aureus;Nitzan;FEMS Microbiol Lett,1987

5. Hemolysis of human erythrocytes by hemin. The role of hemin in erythrocyte autohemolysis;Iamaĭkina;Biofizika,1994

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