Synthesis, Hypoglycaemic, Hypolipidemic and PPARγ Agonist Activities of 5-(2-Alkyl/aryl-6-Arylimidazo[2,1-b][1,3,4]thiadiazol-5-yl)methylene-1,3-Thiazolidinediones-Reference-Cited by-同舟云学术

Synthesis, Hypoglycaemic, Hypolipidemic and PPARγ Agonist Activities of 5-(2-Alkyl/aryl-6-Arylimidazo[2,1-b][1,3,4]thiadiazol-5-yl)methylene-1,3-Thiazolidinediones

Published:2013-07-01 Issue:2 Volume:82 Page:147-155
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Khazi Mohammed Iqbal A.¹,Belavagi Ningaraddi S.¹,Kim Kwang R.²,Gong Young-Dae³,Khazi Imtiyaz Ahmed M.

Affiliation:

1. Department of Chemistry; Karnatak University; Dharwad; India

2. Bio-Organic Science Division; Korea Research Institute of Chemical Technology; Daejeon; Korea

3. Center for Innovative Drug Library Research, Science College; Dongguk University; Seoul; Korea

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12140/fullpdf

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3. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ);Lehman;J Biol Chem,1995

4. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation;Kliewer;Cell,1995

5. The structure-activity relationship between peroxisome proliferator-activated receptor γ agonism and the antihyperglycemic activity of thiazolidinediones;Willson;J Med Chem,1996

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