Design and Synthesis of a Tetrahydroisoquinoline-Based Hydroxamate Derivative (ZYJ-34v), An Oral Active Histone Deacetylase Inhibitor with Potent Antitumor Activity-Reference-Cited by-同舟云学术

Design and Synthesis of a Tetrahydroisoquinoline-Based Hydroxamate Derivative (ZYJ-34v), An Oral Active Histone Deacetylase Inhibitor with Potent Antitumor Activity

Published:2013-07-01 Issue:2 Volume:82 Page:125-130
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Zhang Yingjie¹,Liu Chunxi²,Chou C. James³,Wang Xuejian⁴,Jia Yuping⁵,Xu Wenfang¹

Affiliation:

1. Department of Medicinal Chemistry; School of Pharmacy; Shandong University; Ji'nan; Shandong; 250012; China

2. Department of Pharmaceutics; School of Pharmacy; Shandong University; Ji'nan; Shandong; 250012; China

3. Department of Drug Discovery and Biomedical Sciences; South Carolina College of Pharmacy; Medical University of South Carolina; Charleston; SC; 29425; USA

4. Postdoctoral Workstation; Weifang Biomedical Industry Park Management Office; Weifang; Shandong; 261205; China

5. Key Laboratory of Chemical Drugs; Shandong Institute of Pharmaceutical Industry; Jinan; Shandong; 250101; China

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12144/fullpdf

Reference15 articles.

1. Epigenetic opportunities and challenges in cancer;Best;Drug Discov Today,2010

2. Histone deacetylase: a regulator of transcription;Wolffe;Science,1996

3. Nuclear histone acetylases and deacetylases and transcriptional regulation: HATs off to HDACs;Hassig;Curr Opin Chem Biol,1997

4. Histone acetylases and deacetylases in cell proliferation;Kouzarides;Curr Opin Genet Dev,1999

5. Acetylation and deacetylation of non-histone proteins;Glozak;Gene,2005

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