Flexible enzymatic activation of artificial polyketide extender units by Streptomyces cinnamonensis into the monensin biosynthetic pathway
Author:
Affiliation:
1. Organische Chemie 1; Fakultät für Chemie und Biochemie; Ruhr-Universität Bochum; Bochum Germany
2. Spectral Service; Köln Germany
Funder
Cluster of Excellence RESOLV
Deutsche Forschungsgemeinschaft
Publisher
Wiley
Subject
Applied Microbiology and Biotechnology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/lam.13039/fullpdf
Reference21 articles.
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3. Cloning and analysis of the promoter region of the erythromycin resistance gene (ermE) of Streptomyces erythraeus;Bibb;Gene,1985
4. Predicted incorporation of non-native substrates by a polyketide synthase yields bioactive natural product derivatives;Bravo-Rodriguez;ChemBioChem,2014
5. Substrate flexibility of a mutated acyltransferase domain and implications for polyketide biosynthesis;Bravo-Rodriguez;Chem Biol,2015
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