Antibiotic use for airway infections in Norwegian children—A national register‐based study

Author:

Rydland Eva12,Høye Sigurd3,Størdal Ketil145ORCID

Affiliation:

1. Department of Pediatrics Østfold Hospital Trust Grålum Norway

2. Faculty of Medicine, Institute of Clinical Medicine University of Oslo Oslo Norway

3. Antibiotic Centre for Primary Care, Department of General Practice, Faculty of Medicine, Institute of Health and Society University of Oslo Oslo Norway

4. Department of Pediatric Research University of Oslo Oslo Norway

5. Division of Pediatric and Adolescent Medicine Oslo University Hospital Oslo Norway

Abstract

AbstractAimRespiratory tract infections (RTIs) are major contributors to childhood antibiotic use. We aimed to investigate geographical and temporal trends in the prescription of antibiotics and consultations for RTIs in children <18 years living in Norway from 2010 to 2017.MethodsIn a nationwide observational study, we analysed antibiotic prescriptions from the Norwegian Prescription Database and reimbursed contacts from primary care physicians. We limited the study to airway antibiotics and diagnostic codes indicating RTIs.ResultsAntibiotic prescriptions due to an RTI varied from 75 to 134 per 1000 consultation due to RTI across counties in Norway (relative risk 1.79, 95% CI 1.68–1.90 for highest compared to lowest). The use of health care varied from 414 to 585 consultations for RTI per 1000 inhabitant/year (relative risk 1.43, 95% CI 1.41–1.44 for highest compared to lowest). From 2010 to 2017, we observed a 21% reduction in antibiotic prescriptions per RTI consultation and of 6% for the number of consultations for an RTI. At the county level, the use of health care was positively associated with the proportion of RTIs that resulted in antibiotic prescription.ConclusionWe found a reduction in doctors' antibiotic prescription and the use of health care for RTIs, and a variation across counties.

Publisher

Wiley

Subject

General Medicine,Pediatrics, Perinatology and Child Health

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