Relationship between cortical and medullary thickness and glomerular filtration rate among living kidney donors

Author:

Kuhnel Lukas1,Vu Thomas1,Wood Simon T.12,Francis Ross S.12,Trnka Peter13,Ellis Robert J.12ORCID

Affiliation:

1. Faculty of Medicine University of Queensland Brisbane Queensland Australia

2. Princess Alexandra Hospital Metro South Hospital and Health Service Brisbane Queensland Australia

3. Department of Nephrology Queensland Children's Hospital Brisbane Queensland Australia

Abstract

AbstractThe relationship between the kidney cortex and medulla is not well understood in healthy populations. This study characterised the relationship between cortical/medullary thickness and measured glomerular filtration rate (GFR) in 390 living kidney donors. A positive relationship was observed between medullary, but not cortical, thickness and GFR. We propose that this reflects a correlation between juxtamedullary nephron number and GFR.

Publisher

Wiley

Subject

Internal Medicine

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