Human steroid and oxysterol 7α-hydroxylase CYP7B1: substrate specificity, azole binding and misfolding of clinically relevant mutants
Author:
Affiliation:
1. Institute of Bioorganic Chemistry NAS of Belarus; Minsk Belarus
2. Structural Genomics Consortium; University of Toronto; Canada
Publisher
Wiley
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/febs.12733/fullpdf
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3. Characterization of the dehydroepiandrosterone (DHEA) metabolism via oxysterol 7alpha-hydroxylase and 17-ketosteroid reductase activity in the human brain;Steckelbroeck;J Neurochem,2002
4. 25-Hydroxycholesterol secreted by macrophages in response to toll-like receptor activation suppresses immunoglobulin A production;Bauman;Proc Natl Acad Sci USA,2009
5. Early onset of puberty and early ovarian failure in CYP7B1 knockout mice;Omoto;Proc Natl Acad Sci USA,2005
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