Substrate scope and selectivity in offspring to an enzyme subjected to directed evolution
Author:
Affiliation:
1. Department of Chemistry - BMC; Uppsala University; Sweden
2. Structural Bioinformatics Laboratory; Åbo Akademi University; Turku Finland
Funder
Swedish Research Council
Publisher
Wiley
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/febs.12791/fullpdf
Reference31 articles.
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4. Similarity of Escherichia coli propanediol oxidoreductase (fucO product) and an unusual alcohol dehydrogenase from Zymomonas mobilis and Saccharomyces cerevisiae;Conway;J Bacteriol,1989
5. Functional characterization of a stereospecific diol dehydrogenase, FucO, from Escherichia coli: substrate specificity, pH dependence, kinetic isotope effects and influence of solvent viscosity;Blikstad;J Mol Catal B Enzym,2010
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