Response to mitogen‐activated protein kinase inhibition of neurodegeneration in Langerhans cell histiocytosis monitored by cerebrospinal fluid neurofilament light as a biomarker: a pilot study

Author:

Henter Jan‐Inge12ORCID,Kvedaraite Egle134ORCID,Martín Muñoz Daniel56,Cheng Munthe‐Kaas Monica7,Zeller Bernward7ORCID,Nystad Tove A.8,Björklund Caroline9,Donnér Isabella10,Lourda Magda13ORCID,Zetterberg Henrik11121314,Blennow Kaj1112,Herold Nikolas12,Gavhed Désirée12,von Bahr Greenwood Tatiana12ORCID

Affiliation:

1. Childhood Cancer Research Unit Department of Women’s and Children’s Health Karolinska Institutet StockholmSweden

2. Pediatric Oncology Astrid Lindgrens Children’s Hospital Karolinska University Hospital StockholmSweden

3. Center for Infectious Medicine Department of Medicine Huddinge Karolinska Institutet StSweden

4. Department of Clinical Pathology Karolinska University Laboratory StockholmSweden

5. Department of Clinical Neuroscience Karolinska Institutet StockholmSweden

6. Department of Neuroradiology Karolinska University Hospital Stockholm Sweden

7. Department of Pediatric Hematology and Oncology Oslo University Hospital OsloNorway

8. Department of Pediatrics Division of Child and Adolescent Health University Hospital of North‐Norway Tromsø Norway

9. Department of Pediatric Hematology and Oncology Umeå University Hospital UmeåSweden

10. Hallands Hospital HalmstadSweden

11. Clinical Neurochemistry Laboratory Sahlgrenska University Hospital MölndalSweden

12. Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology the Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden

13. UK Dementia Research Institute at UCL London UK

14. Department of Neurodegenerative Disease UCL Institute of Neurology London UK

Funder

Barncancerfonden

Stockholms Läns Landsting

Cancerfonden

Insamlingsstiftelsen Cancer- och Allergifonden

Publisher

Wiley

Subject

Hematology

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