High quality (certainty) evidence changes less often than low‐quality evidence, but the magnitude of effect size does not systematically differ between studies with low versus high‐quality evidence

Author:

Djulbegovic Benjamin1ORCID,Ahmed Muhammad Muneeb2ORCID,Hozo Iztok3,Koletsi Despina4,Hemkens Lars567,Price Amy8,Riera Rachel9,Nadanovsky Paulo10,Santos Ana Paula Pires11,Melo Daniela12,Pathak Ranjan13,Pacheco Rafael Leite14,Fontes Luis Eduardo1415,Miranda Enderson15,Nunan David1516

Affiliation:

1. Department of Computational & Quantitative Medicine Beckman Research Institute, City of Hope Duarte California USA

2. Michael G. DeGroote School of Medicine McMaster University Hamilton Ontario Canada

3. Department of Mathematics Indiana University Northwest Gary Indiana USA

4. Clinic of Orthodontics and Pediatric Dentistry, Center of Dental Medicine University of Zurich Zurich Switzerland

5. Department of Clinical Research, University of Basel, Basel Institute for Clinical Epidemiology & Biostatistics University Hospital Basel Basel Switzerland

6. Meta‐Research Innovation Center at Stanford (METRICS) Stanford University Stanford California USA

7. Meta‐Research Innovation Center Berlin (METRIC‐B) Berlin Institute of Health Berlin Germany

8. Anesthesia Informatics and Media Lab Stanford University Stanford California USA

9. Universidade Federal de São Paulo Escola Paulista de Medicina, Brazil (Unifesp) São Paulo Brazil

10. Department of Epidemiology and Quantitative Methods in Health, National School of Public Health, Fundação Oswaldo Cruz (FIOCRUZ) ‐ Department of Epidemiology, Institute of Social Medicine Universidade do Estado do Rio de Janeiro (UERJ) Rio de Janeiro Brazil

11. Department of Pharmaceutical Sciences Universidade Federal de São Paulo (Unifesp) Rio de Janeiro Brazil

12. Department of Community and Preventive Dentistry, Faculty of Dentistry Universidade do Estado do Rio de Janeiro (UERJ) Rio de Janeiro Brazil

13. Department of Medical Oncology and Therapeutics Research City of Hope Duarte California USA

14. Centro Universitário São Camilo, Researcher at the Center of Health Technology Assessment Hospital Sirio‐Libanês São Paulo Brazil

15. Department of Intensive Care, and Emergency Medicine at Faculdade de Medicina de Petrópolis, in Petrópolis Rio de Janeiro Brazil

16. Kellogg College University of Oxford Oxford UK

Funder

Agency for Healthcare Research and Quality

Publisher

Wiley

Subject

Public Health, Environmental and Occupational Health,Health Policy

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