Daunorubicin Down-Regulates the Expression of Stem Cell Markers and Factors Involved in Stem Cell Migration and Homing in Rat Heart in Subchronic but not Acute Cardiomyopathy

Author:

Srankova Jasna1,Doka Gabriel1,Pivackova Lenka1,Mesarosova Lucia1,Kyselovic Jan1,Klimas Jan1,Krenek Peter1

Affiliation:

1. Comenius University in Bratislava; Faculty of Pharmacy; Department of Pharmacology and Toxicology; Bratislava Slovak Republic

Funder

Agentúra na Podporu Výskumu a Vývoja

Vedecká Grantová Agentúra MŠVVaŠ SR a SAV

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Reference39 articles.

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2. Identification of the molecular basis of doxorubicin-induced cardiotoxicity;Zhang;Nat Med,2012

3. Unbalanced upregulation of ryanodine receptor 2 plays a particular role in early development of daunorubicin cardiomyopathy;Kucerova;Am J Transl Res,2015

4. Anthracycline-induced cardiotoxicity: overview of studies examining the roles of oxidative stress and free cellular iron;Simůnek;Pharmacol Rep PR,2009

5. Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation;Ichikawa;J Clin Invest,2014

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