1. Medicinal Plants Research Center; Federal University of Piauí; Teresina PI Brazil
2. Department of Biophysics and Physiology; Federal University of Piauí; Teresina PI Brazil
3. Department of Chemistry; Federal University of Piauí; Teresina PI Brazil
4. Department of Biochemistry and Pharmacology; Federal University of Piauí; Teresina PI Brazil