The oral iron chelator deferasirox inhibits NF-κB mediated gene expression without impacting on proximal activation: implications for myelodysplasia and aplastic anaemia-Reference-Cited by-同舟云学术

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The oral iron chelator deferasirox inhibits NF-κB mediated gene expression without impacting on proximal activation: implications for myelodysplasia and aplastic anaemia

Published:2014-10-01 Issue:4 Volume:168 Page:576-582
ISSN:0007-1048
Container-title:British Journal of Haematology
language:en
Short-container-title:Br J Haematol

Author:

Banerjee Ashish¹²^ORCID,Mifsud Nicole A.³,Bird Robert⁴⁵,Forsyth Cecily⁶,Szer Jeff⁷,Tam Constantine⁸,Kellner Sybil⁹,Grigg Andrew¹⁰,Motum Penelope¹¹,Bentley Mark¹²,Opat Stephen¹³,Grigoriadis George¹²¹³¹⁴

Affiliation:

1. Centre for Cancer Research; MIMR-PHI Institute of Medical Research; Clayton Vic. Australia

2. Centre for Inflammatory Diseases; Monash University; Clayton Vic. Australia

3. Departments of Medicine and Allergy, Immunology and Respiratory Medicine; Monash University; Clayton Vic. Australia

4. Haematology; Princess Alexandra Hospital; Brisbane Qld Australia

5. School of Medicine; Griffith University; Brisbane Qld Australia

6. Haematology; Jarrett Street Specialist Centre; North Gosford NSW Australia

7. Clinical Haematology; Royal Melbourne Hospital; Melbourne Vic. Australia

8. Haematology; Peter MacCallum Cancer Centre; East Melbourne Vic. Australia

9. Haematology; Cotton Tree Specialist Centre; Cotton Tree Qld Australia

10. Department of Clinical Haematology; Austin Hospital; Heidelberg Vic. Australia

11. Haematology Department; Liverpool Hospital; Liverpool NSW Australia

12. Haematology; Queensland Haematology and Oncology Group; Brisbane Qld Australia

13. Clinical Haematology; Monash Health; Clayton Vic. Australia

14. Department of Haematology; Alfred Health; Melbourne Australia

Funder

Novartis

Publisher

Wiley

Subject

Hematology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bjh.13151/fullpdf

Reference27 articles.

1. Deferasirox for transfusion-dependent patients with myelodysplastic syndromes: safety, efficacy, and beyond (GIMEMA MDS0306 Trial);Angelucci;European Journal of Haematology,2014

2. Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells;Banerjee;Proceedings of the National Academy of Sciences of the United States of America,2006

3. NF-kappaB1 and c-Rel cooperate to promote the survival of TLR4-activated B cells by neutralizing Bim via distinct mechanisms;Banerjee;Blood,2008

4. NF-kappaB as a potential therapeutic target in myelodysplastic syndromes and acute myeloid leukemia;Breccia;Expert Opinion on Therapeutic Targets,2010

5. The genetic basis of myelodysplasia and its clinical relevance;Cazzola;Blood,2013

Cited by 29 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Impact of Iron Overload and Iron Chelation with Deferasirox on Outcomes of Patients with Severe Aplastic Anemia after Allogeneic Hematopoietic Stem Cell Transplantation;Transplantation and Cellular Therapy;2023-08

2. The effectiveness of deferasirox to prevent from the occurrence of liver fibrosis in balb/c mice with iron overload;Bangladesh Journal of Medical Science;2023-01-01

3. Excessive Iron in Diets Promotes Kidney Fibrosis Via Disordering the Inflammation Factors in Sheep;SSRN Electronic Journal;2022

4. Iron overload-induced oxidative stress in myelodysplastic syndromes and its cellular sequelae;Critical Reviews in Oncology/Hematology;2021-07

5. Acquired severe aplastic anaemia: how medical therapy evolved in the 20th and 21st centuries;British Journal of Haematology;2021-04-14

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