Depletion of Rictor, an essential protein component of m TORC 2, decreases male lifespan-Reference-Cited by-同舟云学术

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Depletion of Rictor, an essential protein component of m TORC 2, decreases male lifespan

Published:2014-07-25 Issue:5 Volume:13 Page:911-917
ISSN:1474-9718
Container-title:Aging Cell
language:en
Short-container-title:Aging Cell

Author:

Lamming Dudley W.¹²³⁴⁵,Mihaylova Maria M.³⁴⁵⁶⁷,Katajisto Pekka³⁴⁵⁶⁷,Baar Emma L.¹²,Yilmaz Omer H.³⁴⁵⁶⁷,Hutchins Amanda³⁴⁵⁶⁷,Gultekin Yetis³⁴⁵⁶⁷,Gaither Rachel³⁴⁵⁶⁷,Sabatini David M.³⁴⁵⁶⁷

Affiliation:

1. Department of Medicine University of Wisconsin Madison WI 53705USA

2. William S. Middleton Memorial Veterans Hospital Madison WI 53705USA

3. Whitehead Institute for Biomedical Research Cambridge MA 02142USA

4. Department of Biology MIT Cambridge MA 02139 USA

5. Howard Hughes Medical Institute MIT Cambridge MA 02139 USA

6. Broad Institute of Harvard and MIT Seven Cambridge Center Cambridge MA 02142USA

7. The David H. Koch Institute for Integrative Cancer Research at MIT Cambridge MA 02139USA

Funder

National Institute on Aging

American Federation for Aging Research

Ellison Medical Foundation

Howard Hughes Medical Institute

Damon Runyon Cancer Research Foundation

American Diabetes Association

Publisher

Wiley

Subject

Cell Biology,Aging

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/acel.12256

Reference32 articles.

1. Therapeutic Trial of Metformin and Bortezomib in a Mouse Model of Tuberous Sclerosis Complex (TSC)

2. Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster

3. Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKCα, but Not S6K1

4. mTOR Complex 2 Is Required for the Development of Prostate Cancer Induced by Pten Loss in Mice

5. Sirolimus Therapy Predisposes to New-Onset Diabetes Mellitus After Renal Transplantation: A Long-Term Analysis of Various Treatment Regimens

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