TCR deep sequencing of transgenic RAG-1-deficient mice reveals endogenous TCR recombination: a cause for caution-Reference-Cited by-同舟云学术

TCR deep sequencing of transgenic RAG-1-deficient mice reveals endogenous TCR recombination: a cause for caution

Published:2018-03-24 Issue:6 Volume:96 Page:642-645
ISSN:0818-9641
Container-title:Immunology and Cell Biology
language:en
Short-container-title:Immunol Cell Biol

Author:

McGuire Helen M¹²³^ORCID,Watkins Thomas S⁴⁵⁶,Field Matthew⁴,Taylor Sarah⁷,Yasuyama Nao⁷,Farmer Andrew⁷,Miles John J⁴⁵⁶⁸,Fazekas de St. Groth Barbara²³

Affiliation:

1. Centenary Institute; Camperdown NSW Australia

2. Discipline of Pathology; School of Medical Sciences; Charles Perkins Centre; University of Sydney; NSW Australia

3. Ramaciotti Facility for Human Systems Biology; Charles Perkins Centre; University of Sydney; NSW Australia

4. Centre for Biodiscovery and Molecular Development of Therapeutics; AITHM; James Cook University; Cairns QLD Australia

5. QIMR Berghofer Medical Research Institute; Brisbane QLD Australia

6. Faculty of Medicine; The University of Queensland; Brisbane QLD Australia

7. Takara Bio USA, Inc.; 1290 Terra Bella Ave, Mountain View CA USA

8. Institute of Infection and Immunity; Cardiff University School of Medicine; Heath Park Cardiff UK

Funder

National Health and Medical Research Council

Publisher

Wiley

Subject

Cell Biology,Immunology,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/imcb.12033/fullpdf

Reference7 articles.

1. T-cell-specific deletion of T-cell receptor transgenes allows functional rearrangement of endogenous a- and b-genes;Bluthman;Nature,1988

2. Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes;Shinkai;Science,1993

3. TCR-mediated involvement of CD4+ transgenic T cells in spontaneous inflammatory bowel disease in lymphopenic mice;Koh;J Immunol,1999

4. Endogenous TCR recombination in TCR Tg single RAG-deficient mice uncovered by robust in vivo T cell activation and selection;Montaudouin;PLoS One,2010

5. Cutting Edge: rag deletion in peripheral T cells blocks TCR revision;Hale;J Immunol,2010

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