Molar‐incisor‐malformation in a paediatric cancer patient: Case report

Author:

Tosiou Athina1,Mastrokalou Andriana1,Prasad Hari S.2,Tosios Konstantinos I.3ORCID,Koutlas Ioannis G.2ORCID

Affiliation:

1. Dental School, University of Athens Athens Greece

2. Division of Oral and Maxillofacial Pathology School of Dentistry, University of Minnesota Minneapolis Minnesota USA

3. Department of Oral Pathology and Medicine, and Hospital Dentistry Dental School, University of Athens Athens Greece

Abstract

AbstractAimTo report a case of molar‐incisor‐malformation (MIM) in a 7‐year‐old boy with a history of congenital infantile fibrosarcoma of the upper chest, which was surgically treated, without adjuvant radio/chemotherapy.Material and MethodsThe boy presented with mobility and pain on percussion of the permanent mandibular first molars. The radiographic features were suggestive of MIM. Both teeth were extracted and processed for conventional light microscopic examination and non‐decalcified ground sections.ResultsThe microscopic features confirmed the diagnosis of MIM. Regular follow‐up was recommended.ConclusionsMedical interventions during hospitalization for cancer treatment, other than chemo/radiotherapy, may cause MIM by adversely affecting the function of Hertwig's epithelial root sheath. Regular dental screening in paediatric cancer patients may reveal more MIM cases and help in elucidating its pathogenesis.

Publisher

Wiley

Subject

Oral Surgery,Surgery

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