PGC-1α4 gene expression is suppressed by the IL-6-MEK-ERK 1/2 MAPK signalling axis and altered by resistance exercise, obesity and muscle injury-Reference-Cited by-同舟云学术

PGC-1α4 gene expression is suppressed by the IL-6-MEK-ERK 1/2 MAPK signalling axis and altered by resistance exercise, obesity and muscle injury

Published:2016-11-25 Issue:2 Volume:220 Page:275-288
ISSN:1748-1708
Container-title:Acta Physiologica
language:en
Short-container-title:Acta Physiol

Author:

Brown J. L.¹,Rosa-Caldwell M. E.¹,Lee D. E.¹,Brown L. A.²,Perry R. A.²,Shimkus K. L.³,Blackwell T. A.¹,Fluckey J. D.³,Carson J. A.⁴,Dridi S.⁵,Washington T. A.²,Greene N. P.¹

Affiliation:

1. Integrative Muscle Metabolism Laboratory; Human Performance Laboratory; Department of Health; Human Performance and Recreation; University of Arkansas; Fayetteville AR USA

2. Exercise Muscle Biology Laboratory; Human Performance Laboratory; Department of Health; Human Performance and Recreation; University of Arkansas; Fayetteville AR USA

3. Muscle Biology Laboratory; Department of Health & Kinesiology; Texas A&M University; College Station TX USA

4. Integrative Muscle Biology Laboratory; Department of Exercise Science; University of South Carolina; Columbia SC USA

5. Center of Excellence for Poultry Science; University of Arkansas; Fayetteville AR USA

Funder

Cell and Molecular Biology Interdisciplinary Graduate Program at the University of Arkansas Fayetteville

Publisher

Wiley

Subject

Physiology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/apha.12826/fullpdf

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4. Tumor necrosis factor-α regulates distinct molecular pathways and gene networks in cultured skeletal muscle cells;Bhatnagar;PLoS One,2010

5. JAK/STAT3 pathway inhibition blocks skeletal muscle wasting downstream of IL-6 and in experimental cancer cachexia;Bonetto;Am J Physiol Endocrinol Metab,2012

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