Predictors of serious adverse events and non‐response in cirrhotic patients with primary biliary cholangitis treated with obeticholic acid

Author:

De Vincentis Antonio1ORCID,D'Amato Daphne2,Cristoferi Laura3,Gerussi Alessio3,Malinverno Federica3,Lleo Ana4ORCID,Colapietro Francesca4ORCID,Marra Fabio5ORCID,Galli Andrea6,Fiorini Cecilia6,Coco Barbara7,Brunetto Maurizia7ORCID,Niro Grazia Anna8,Cotugno Rosa8,Saitta Carlo9,Cozzolongo Raffaele10,Losito Francesco10,Giannini Edoardo Giovanni11ORCID,Labanca Sara11,Marzioni Marco12,Marconi Giulia12,Morgando Anna2,Pellicano Rinaldo2,Vanni Ester2,Cazzagon Nora13,Floreani Annarosa13,Chessa Luchino14ORCID,Morelli Olivia15,Muratori Luigi16ORCID,Pellicelli Adriano17ORCID,Pompili Maurizio18,Ponziani Francesca18ORCID,Tortora Annalisa18,Rosina Floriano19,Russello Maurizio20,Cannavò Mariarita20,Simone Loredana21,Storato Silvia22,Viganò Mauro23ORCID,Abenavoli Ludovico24,D'Antò Maria25,De Gasperi Elisabetta26ORCID,Distefano Marco27,Scifo Gaetano27,Zolfino Teresa28,Calvaruso Vincenza29ORCID,Cuccorese Giuseppe30,Palitti Valeria Pace31,Sacco Rodolfo32,Bertino Gaetano33,Frazzetto Evelise33,Alvaro Domenico34,Mulinacci Giacomo3,Palermo Andrea3,Scaravaglio Miki3,Terracciani Francesca1,Galati Giovanni1,Ronca Vincenzo3,Zuin Massimo3536,Claar Ernesto37,Izzi Antonio38,Picardi Antonio1,Invernizzi Pietro3ORCID,Vespasiani‐Gentilucci Umberto1ORCID,Carbone Marco3ORCID,Feletti Valentina,Mussetto Alessandro,Venere Rosanna,Bernaccioni Giulia,Graciella Pigozzi Marie,Fagiuoli Stefano,Terreni Natalia,Pozzoni Pietro,Baiocchi Leonardo,Grassi Giuseppe,Vinci Maria,Bellia Valentina,Boldizzoni Roberto,Casella Silvia,Omazzi Barbara,Poggi Guido,

Affiliation:

1. Internal Medicine and Hepatology University Campus Bio‐Medico of Rome Rome Italy

2. Gastroenterology Unit, Città della salute e della scienza Turin Italy

3. Division of Gastroenterology, Centre for Autoimmune Liver Diseases, Department of Medicine and Surgery University of Milano‐Bicocca, European Reference Network on Hepatological Diseases (ERN RARE‐LIVER), San Gerardo Hospital Monza Italy

4. Internal Medicine and Hepatology, Humanitas Clinical and Research Center IRCCS Humanitas University Milan Italy

5. Internal Medicine and Hepatology Unit, Department of Experimental and Clinical Medicine University of Firenze Firenze Italy

6. Department of Experimental and Clinical Biochemical Sciences University of Florence Florence Italy

7. Hepatology Unit, University Hospital of Pisa Pisa Italy

8. Gastroenterology Unit, Fondazione Casa Sollievo Della Sofferenza IRCCS San Giovanni Rotondo Italy

9. Division of Medicine and Hepatology University Hospital of Messina “Policlinico G. Martino” Messina Italy

10. Gastroenterology Unit National Institute of Gastroenterology “S de Bellis” Research Hospital Castellana Grotte Italy

11. Gastroenterology Unit, Department of Internal Medicine University of Genova, IRCCS Ospedale Policlinico San Martino Genova Italy

12. Clinic of Gastroenterology and Hepatology Università Politecnica delle Marche Ancona Italy

13. Gastroenterology Unit, Department of Surgery, Oncology and Gastroenterology Padua University Hospital Padua Italy

14. Liver Unit, University Hospital of Cagliari Cagliari Italy

15. Clinic of Gastroenterology and Hepatology, Department of Medicine Università degli Studi di Perugia Perugia Italy

16. DIMEC Università di Bologna, Policlinico di Sant'Orsola Bologna Italy

17. Liver Unit, San Camillo Hospital Rome Italy

18. Internal Medicine and Hepatology Unit, Policlinico Gemelli Sapienza University Rome Italy

19. Medical Team Torino Torino Italy

20. Liver Unit, Arnas Garibaldi Catania Italy

21. Department of Gastroenterology University Hospital Sant'Anna Ferrara Italy

22. IRCCS Sacro Cuore Institute Don Calabria, Gastroenterology Negrar Italy

23. Hepatology Unit, San Giuseppe Hospital Milan Italy

24. Department of Health Sciences University “Magna Graecia” of Catanzaro Italy

25. Hepatology Unit, Santa Maria delle Grazie Hospital Pozzuoli Italy

26. Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico – Division of Gastroenterology and Hepatology – CRC “A.M. and A. Migliavacca” Center for Liver Disease Milan Italy

27. Department of Infectious Diseases Umberto I Hospital Syracuse Italy

28. Department of Gastroenterology Brotzu Hospital Cagliari Italy

29. Gastroenterology and Hepatology Unit University of Palermo Palermo Italy

30. Internal Medicine Ospedale “R. Dimiccoli” Barletta Italy

31. Hepatology Unit, Santo Spirito Hospital Pescara Italy

32. Gastroenterology Unit, Ospedali Riuniti Foggia Italy

33. Gastroenterology and Hepatology Unit University Hospital Policlinico Vittorio Emanuele Catania Italy

34. Department of Translational and Precision Medicine University La Sapienza Rome Italy

35. Liver and Gastroenterology Unit, Department of Health Sciences Universita’ degli Studi di Milano Milan Italy

36. ASST Santi Paolo e Carlo University Hospital San Paolo Milan Italy

37. Department of Hepatology Betania Hospital Napoli Italy

38. Department of Infectious Diseases D. Cotugno Hospital Napoli Italy

Publisher

Wiley

Subject

Hepatology

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