DKK1 drives immune suppressive phenotypes in intrahepatic cholangiocarcinoma and can be targeted with anti‐DKK1 therapeutic DKN ‐01

Author:

Jarman Edward J.1ORCID,Horcas‐Lopez Marta2,Waddell Scott H.1ORCID,MacMaster Stephanie1,Gournopanos Konstantinos1,Soong Daniel Y. H.2,Musialik Kamila I.1,Tsokkou Panagiota1,Ng Minn‐E1,Cambridge William A.13,Wilson David H.1,Kagey Michael H.4,Newman Walter4,Pollard Jeffrey W.2ORCID,Boulter Luke1ORCID

Affiliation:

1. MRC Human Genetics Unit Institute of Genetics and Cancer, University of Edinburgh Edinburgh UK

2. MRC Centre for Reproductive Health Queen's Medical Research Institute, The University of Edinburgh Edinburgh UK

3. Department of Clinical Surgery University of Edinburgh, Little France Crescent Edinburgh UK

4. Leap Therapeutics Cambridge Massachusetts USA

Funder

Cancer Research UK

Royal College of Surgeons of Edinburgh

Wellcome Trust

Publisher

Wiley

Subject

Hepatology

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