Central nervous system effects of the histamine‐3 receptor antagonist CEP‐26401, in comparison with modafinil and donepezil, after a single dose in a cross‐over study in healthy volunteers-Reference-Cited by-同舟云学术

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Central nervous system effects of the histamine‐3 receptor antagonist CEP‐26401, in comparison with modafinil and donepezil, after a single dose in a cross‐over study in healthy volunteers

Published:2019-03-14 Issue:5 Volume:85 Page:970-985
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:Br J Clin Pharmacol

Author:

Baakman Anne C.¹^ORCID,Zuiker Rob¹,Gerven Joop M.A.¹,Gross Nicholas²,Yang Ronghua²,Fetell Michael²,Gershon Ari³⁴,Gilgun‐Sherki Yossi⁵,Hellriegel Edward⁶,Spiegelstein Ofer⁷

Affiliation:

1. Centre for Human Drug Research Leiden Netherlands

2. Research and Development Teva Pharmaceuticals Frazer Philadelphia USA

3. Global Patient Safety and Pharmacovigilance, Teva Pharmaceuticals Petah Tikva Israel

4. Formerly Global Patient Safety and Pharmacovigilance, Teva Pharmaceuticals Petah Tikva Israel

5. Formerly Research and Development Teva Pharmaceuticals Netanya Israel

6. Research and Development Teva Pharmaceuticals West Chester Pennsylvania USA

7. Research and Development Teva Pharmaceuticals Netanya Israel

Funder

Teva Pharmaceutical Industries

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bcp.13885

Reference67 articles.

1. Histamine H3 Receptor as a Drug Discovery Target

2. The histamine H3 receptor as a therapeutic drug target for CNS disorders

3. Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor

4. Autoinhibition of histamine synthesis mediated by presynaptic H3-receptors

5. Histaminergic and glycinergic modulation of GABA release in the vestibular nuclei of normal and labyrinthectomised rats

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1. Administration of oxathridine, a first‐in‐class histamine‐3 receptor partial agonist in healthy male volunteers: Central nervous system depression and pseudo‐hallucinations;British Journal of Clinical Pharmacology;2023-10-11

2. Pharmacological characterization of the selective orexin-1 receptor antagonist JNJ-61393215 in healthy volunteers;Journal of Psychopharmacology;2023-05-11

3. Translatability of preclinical to early clinical tolerable and pharmacologically active dose ranges for central nervous system active drugs;Translational Psychiatry;2023-03-01

4. Central nervous system effects of TAK-653, an investigational alpha-amino-3-hydroxy-5-methyl-4-isoxazole receptor (AMPAR) positive allosteric modulator in healthy volunteers;Translational Psychiatry;2022-09-24

5. The functional effects of piperine and piperine plus donepezil on hippocampal synaptic plasticity impairment in rat model of Alzheimer's disease;Life Sciences;2021-01

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