Pregnancy and childbirth in patients with Glanzmann Thrombasthenia-Reference-Cited by-同舟云学术

Pregnancy and childbirth in patients with Glanzmann Thrombasthenia

Published:2024-05-14 Issue: Volume: Page:
ISSN:0007-1048
Container-title:British Journal of Haematology
language:en
Short-container-title:Br J Haematol

Author:

Rottenstreich Amihai¹²³⁴^ORCID,Coller Barry S.¹

Affiliation:

1. Laboratory of Blood and Vascular Biology Rockefeller University New York City New York USA

2. Division of Maternal‐Fetal Medicine, Department of Obstetrics and Gynecology, Zucker School of Medicine at Hofstra/Northwell New York City New York USA

3. Department of Obstetrics and Gynecology Hadassah‐Hebrew University Medical Center Jerusalem Israel

4. Faculty of Medicine, Hebrew University of Jerusalem Jerusalem Israel

Abstract

SummaryGlanzmann thrombasthenia (GT) is a rare inherited platelet bleeding disorder caused by a quantitative and/or qualitative defect of the αIIbβ3 integrin. Pregnancy and delivery pose special challenges as they entail increased risks of both maternal and foetal bleeding that may be life‐threatening. Multidisciplinary management throughout the preconception, intrapartum and peripartum periods is vital to optimize pregnancy outcomes. This Nutshell review focuses on the challenging management of pregnancy and childbirth in patients with GT.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bjh.19528

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