1. Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences L. Sacco "Luigi Sacco" University Hospital, Università di Milano 20157 Italy
2. Department of Pediatrics, V. Buzzi Children's Hospital ASST Fatebenefratelli‐Sacco, Università di Milano via Castelvetro, 32 Milan 20154 Italy
3. Scientific institute IRCCS E. Medea Bosisio Parini LC 23892 Italy