Peri‐operative cardiac arrest in the older frail patient as reported to the 7th National Audit Project of the Royal College of Anaesthetists

Author:

Moppett I. K.12ORCID,Kane A. D.13ORCID,Armstrong R. A.14ORCID,Kursumovic E.15ORCID,Soar J.6ORCID,Cook T. M.57ORCID,

Affiliation:

1. Health Services Research Centre Royal College of Anaesthetists London UK

2. Department of Anaesthesia and Critical Care, Academic Unit of Injury, Rehabilitation and Inflammation University of Nottingham Nottingham UK

3. Department of Anaesthesia James Cook University Hospital, South Tees NHS Foundation Trust Middlesbrough UK

4. Department of Anaesthesia Severn Deanery Bristol UK

5. Department of Anaesthesia and Intensive Care Medicine Royal United Hospitals Bath NHS Foundation Trust Bath UK

6. Department of Anaesthesia and Intensive Care Medicine Southmead Hospital Bristol UK

7. University of Bristol Bristol UK

Abstract

SummaryFrailty increases peri‐operative risk, but details of its burden, clinical features and the risk of, and outcomes following, peri‐operative cardiac arrest are lacking. As a preplanned analysis of the 7th National Audit Project of the Royal College of Anaesthetists, we described the characteristics of older patients living with frailty undergoing anaesthesia and surgery, and those reported to the peri‐operative cardiac arrest case registry. In the activity survey, 1676 (26%) of 6466 patients aged > 65 y were reported as frail (Clinical Frailty Scale score ≥ 5). Increasing age and frailty were both associated with increasing comorbidities and the proportion of surgery undertaken as an emergency. Except in patients who were terminally ill (Clinical Frailty Scale score 9), increasing frailty was associated with an increased proportion of complex or major surgery. The rate of use of invasive arterial blood pressure monitoring was associated with frailty only until Clinical Frailty Scale score 5, and then plateaued or fell. Of 881 cardiac arrests reported to the 7th National Audit Project, 156 (18%) were in patients aged > 65 y and living with frailty, with an estimated incidence of 1 in 1204 (95%CI 1 in 1027–1412) and a mortality rate of 1 in 2020 (95%CI 1 in 1642–2488), approximately 2.6‐fold higher than in adults who were not frail. Hip fracture, emergency laparotomy, emergency vascular surgery and urological surgery were the most common surgical procedures in older patients living with frailty who had a cardiac arrest. We report a high burden of frailty within the surgical population, requiring complex, urgent surgery, and the extent of poorer outcomes of peri‐operative cardiac arrest compared with patients of the same age not living with frailty.

Funder

Royal College of Anaesthetists

Publisher

Wiley

Reference20 articles.

1. The Frailty Syndrome: Definition and Natural History

2. Frailty Guideline Working Group.Guideline for Perioperative Care for People Living with Frailty Undergoing Elective and Emergency Surgery. 2021.https://cpoc.org.uk/sites/cpoc/files/documents/2021‐09/CPOC‐BGS‐Frailty‐Guideline‐2021.pdf(accessed 07/02/2024).

3. Patient characteristics, anaesthetic workload and techniques in the UK: an analysis from the 7th National Audit Project (NAP7) activity survey

4. Age of patients undergoing surgery

5. Projections of multi-morbidity in the older population in England to 2035: estimates from the Population Ageing and Care Simulation (PACSim) model

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