Are serum delta neutrophil index and other inflammatory marker levels different in hyperemesis gravidarum?

Author:

Dal Yusuf1ORCID,Akkuş Fatih2ORCID,Karagün Şebnem1ORCID,Çolak Hatun3ORCID,Coşkun Ayhan1ORCID

Affiliation:

1. Department of Obstetrics and Gynecology, Perinatology Department Mersin University Faculty of Medicine Mersin Turkey

2. Department of Obstetrics and Gynecology, Perinatology Department Necmettin Erbakan University Meram Faculty of Medicine Konya Turkey

3. Department of Obstetrics and Gynecology Mersin University Faculty of Medicine Mersin Turkey

Abstract

AbstractAimHyperemesis gravidarum (HEG) is a condition characterized by nausea and vomiting, fluid electrolyte and acid–base imbalance, dehydration, weight loss, and ketonuria in early pregnancy. The relationship of HEG with inflammation has been studied in many studies. This study aimed to investigate the role of serum delta neutrophil index (DNI), a new inflammatory marker, and other inflammatory markers in demonstrating the disease's presence and severity in HEG patients.Material and MethodThis retrospective study was conducted by accessing the electronic data of 79 pregnant women diagnosed with HEG in a tertiary center between 2017 and 2022 and 100 healthy pregnant women. The demographic characteristics of the study and control groups, as well as the hematological parameters in the complete blood count and the levels of inflammatory markers, were recorded.ResultsThere was no significant difference between the groups regarding hematological parameters, DNI, platelet‐lymphocyte ratio, monocyte‐lymphocyte ratio, and systemic inflammation index (p > 0.05). Neutrophil count and neutrophil‐lymphocyte ratio (NLR) were higher in the HEG group compared to the control group (p < 0.05).ConclusionThis is the first study to determine the relationship between HEG and serum DNI, a new inflammatory marker. We found that serum DNI values in HEG patients were not different from normal pregnancies and did not reflect the presence and severity of the disease. We also found that inflammatory markers other than the NLR were not different from normal pregnancies in HEG patients.

Publisher

Wiley

Subject

Obstetrics and Gynecology

Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3