Phase I study of TZT-1027, a novel synthetic dolastatin 10 derivative and inhibitor of tubulin polymerization, given weekly to advanced solid tumor patients for 3 weeks-Reference-Cited by-同舟云学术

Phase I study of TZT-1027, a novel synthetic dolastatin 10 derivative and inhibitor of tubulin polymerization, given weekly to advanced solid tumor patients for 3 weeks

Published:2009-02 Issue:2 Volume:100 Page:316-321
ISSN:1347-9032
Container-title:Cancer Science
language:en
Short-container-title:

Author:

Yamamoto Nobuyuki,Andoh Masahiro,Kawahara Masaaki,Fukuoka Masahiro,Niitani Hisanobu

Publisher

Wiley

Subject

Cancer Research,Oncology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1349-7006.2008.01023.x/fullpdf

Reference23 articles.

1. Synthesis and antitumor activity of novel dolastatin 10 analogs;Miyazaki;Chem Pharm Bull,1995

2. The isolation and structure of a remarkable marine animal antineoplastic constituent: dolastatin 10;Pettit;J Am Chem Soc,1987

3. Induction of apoptosis in human cancer cells by TZT-1027, an antimicrotubule agent;Watanabe;Apoptosis,2000

4. Characterization of the interaction of TZT-1027a potent antitumour agent, with tubulin;Natsume;Jpn J Cancer Res,2000

5. Antitumor effects of TZT-1027a novel dolastatin 10 derivative, on human tumor xenografts in nude mice;Fujita;Jpn J Cancer Chemother,2000

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