Alterations of the c-kit gene in testicular germ cell tumors
Author:
Publisher
Wiley
Subject
Cancer Research,Oncology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1349-7006.2003.tb01470.x/fullpdf
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1. A loss-of-function mutation of c-kit results in depletion of mast cells and interstitial cells of Cajal, while its gain-of-function mutation results in their oncogenesis
2. The biology of stem cell factor and its receptor C-kit
3. Role of c-kit in mammalian spermatogenesis
4. Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product.
5. Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis
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