In vivoAnti-tumor Activity of a Novel Indolocarbazole Compound, J-107088, on Murine and Human Tumors Transplanted into Mice

Author:

Arakawa Hiroharu,Morita Masashi,Kodera Tsutomu,Okura Akira,Ohkubo Mitsuru,Morishima Hajime,Nishimura Susumu

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference12 articles.

1. Novel antitumor indolocarbazole compound 6-N-formylamino-12, 13-dihydro-1,11 -dihydroxy-13-(β-D-glucopyranosyl)-5H-indolo-[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione (NB-506): induction of topoisomerase I-mediated DNA cleavage and mechanisms of cell line-selective cytotoxicity;Yoshinari;Cancer Res.,1995

2. Novel indolocarbazole compound 6-N-formylamino-2,13-dihydro-1,11-dihydroxy-13-(β-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrole-[3,4-c]carbazole-5,7(6H)-dione (NB-506): its potent antitumor activity in mice;Arakawa;Cancer Res.,1995

3. Mode of action of a new indolocarbazole anticancer agent, J-107088, targeting topoisomerase I;Yoshinari;Cancer Res.,1999

4. Antimetastatic effect of a novel indolocarbazole (NB-506) on IMC-HM murine tumor cells metastasized to the liver;Arakawa;Jpn. J. Cancer Res.,1996

5. Practical synthesis of indolopyrrolocarbazoles;Ohkubo;Tetrahedron,1996

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