GENERATION OF INTRACELLULAR ACTIVE OXYGENS IN MOUSE FM3A CELLS BY 3-HYDROXYAMINO-1-METHYL-5H-PYRIDO[4,3-b]INDOLE, THE ACTIVATED TRP-P-2

Author:

Wataya Yusuke,Yamane Kazuko,Hiramoto Kazuyuki,Ohtsuka Yasuharu,Okubata Yuko,Negishi Kazuo,Hayatsu Hikoya

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference10 articles.

1. Isolation and characterization of active metabolites of tryptophanpyrolysate mutagen, Trp-P-2, formed by rat liver microsomes;Yamazoe;Chem.-Biol. Interact.,1980

2. Activation of a mutagen, 3-amino-1-methyl-5H-pyrido[4,3-b]indole. Identification of 3-hydroxyamino-1-methyl-5H-pyrido [4,3-b]-indole and its reaction with DNA;Hashimoto;Biochem. Biophys. Res. Commun.,1980

3. DNA strand cleavage in vitro by 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]indole, a direct-acting mutagen formed in the metabolism of carcinogenic 3-amino-1-methyl-5H-pyrido[4,3-b]indole;Wakata;Cancer Res.,1985

4. Deoxyribonucleoside triphosphate imbalance: 5-fluorodeoxyuridine-induced DNA double strand breaks in mouse FM3A cells and the mechanism of cell death;Yoshioka;J. Biol. Chem.,1987

5. Infection and nitrobluetetrazolium reduction by neutrophils;Park;Lancet,1968

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