Efficacy and safety of two dosages of canrenone as add-on therapy in hypertensive patients taking ace-inhibitors or angiotensin II receptor blockers and hydrochlorothiazide at maximum dosage in a randomized clinical trial: The ESCAPE-IT trial-Reference-Cited by-同舟云学术

Efficacy and safety of two dosages of canrenone as add-on therapy in hypertensive patients taking ace-inhibitors or angiotensin II receptor blockers and hydrochlorothiazide at maximum dosage in a randomized clinical trial: The ESCAPE-IT trial

Published:2016-12-13 Issue:1 Volume:35 Page:47-54
ISSN:1755-5914
Container-title:Cardiovascular Therapeutics
language:en
Short-container-title:Cardiovasc Ther

Author:

Derosa Giuseppe¹²³,Maffioli Pamela¹²³,D'Avino Maria⁴,Sala Carla⁵,Mugellini Amedeo¹,Vulpis Vito⁶,Felis Salvatore⁷,Guasti Luigina⁸,Sarzani Riccardo⁹,Bestetti Alessandro¹⁰,Vanasia Massimo¹⁰,Gaudio Giovanni¹¹,

Affiliation:

1. Department of Internal Medicine and Therapeutics; University of Pavia; Pavia Italy

2. Diabetes and Metabolic Diseases Unit; Fondazione IRCCS Policlinico S. Matteo; Pavia Italy

3. Centre for Prevention, Surveillance, Diagnosis and Treatment of Rare Diseases; Fondazione IRCCS Policlinico S. Matteo; Pavia Italy

4. Unit for the treatment of Arterial Hypertension; Ospedale Cardarelli; Napoli Italy

5. Unit of Cardiovascular Diseases; Fondazione Policlinico Milano; Milano Italy

6. Unit for the Diagnosis and Treatment of Arterial Hypertension; Department of Internal Medicine; Policlinico di Bari; Bari Italy

7. Cardiology Unit; Ospedale Garibaldi; Catania Italy

8. Research Center on Dyslipidemia, Internal Medicine 1; University of Insubria; Varese Italy

9. Center for the treatment of Hypertension and Cardiovascular Diseases; Ospedali Riuniti di Torrette; Ancona Italy

10. THERABEL GiEnne Pharma; Milano Italy

11. Internal Medicine Division; Ospedale Angelo Bellini; Somma Lombardo Varese Italy

Funder

THERABEL GiEnne Pharma

Publisher

Wiley

Subject

Pharmacology (medical),Cardiology and Cardiovascular Medicine,Pharmacology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/1755-5922.12235/fullpdf

Reference26 articles.

1. Aldosterone antagonists in hypertension and heart failure;Mantero;Ann Endocrinol (Paris),2000

2. The ubiquitous mineralocorticoid receptor: clinical implications;Hawkins;Curr Hypertens Rep,2012

3. The effect of spironolactone on morbidity and mortality in patients with severe heart failure;Pitt;N Engl J Med,1999

4. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction;Pitt;N Engl J Med,2003

5. Eplerenone in patients with systolic heart failure and mild symptoms;Zannad;N Engl J Med.,2011

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Comprehensive analysis of prohibited substances and methods in sports: Unveiling trends, pharmacokinetics, and WADA evolution;Environmental Toxicology and Pharmacology;2024-06

2. Novel Biomarkers of Cardiovascular Disease;Comprehensive Precision Medicine;2024

3. Effect of diuretics on plasma aldosterone and potassium in primary hypertension: A systematic review and meta‐analysis;British Journal of Clinical Pharmacology;2021-12-23

4. Canrenone on cardiovascular mortality in congestive heart failure;Pharmacological Research;2019-03

5. A randomized, double-blind clinical trial of canrenone vs hydrochlorothiazide in addition to angiotensin II receptor blockers in hypertensive type 2 diabetic patients;Drug Design, Development and Therapy;2018-08