Which Types of Regulatory T cells Play Important Roles in Implantation and Pregnancy Maintenance?

Author:

Saito Shigeru1,Shima Tomoko1,Inada Kumiko1,Nakashima Akitoshi1

Affiliation:

1. Department of Obstetrics and Gynecology; University of Toyama; Toyama; Japan

Publisher

Wiley

Subject

Obstetrics and Gynaecology,Reproductive Medicine,Immunology,Immunology and Allergy

Reference37 articles.

1. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases;Sakaguchi;J Immunol,1995

2. Regulatory T cells mediate maternal tolerance to the fetus;Aluvihare;Nat Immunol,2004

3. Decidual and peripheral blood CD4+CD25+ regulatory T cells in early pregnancy subjects and spontaneous abortion cases;Sasaki;Mol Hum Reprod,2004

4. Abnormal T-cell reactivity against paternal antigens in spontaneous abortion: adoptive transfer of pregnancy-induced CD4+CD25+ T regulatory cells prevents fetal rejection in a murine abortion model;Zenclussen;Am J Pathol,2005

5. Proportion of peripheral blood and decidual CD4(+) CD25(bright) regulatory T cells in pre-eclampsia;Sasaki;Clin Exp Immunol,2007

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