GATA6-positive lung adenocarcinomas are associated with invasive mucinous adenocarcinoma morphology, hepatocyte nuclear factor 4α expression, and KRAS mutations

Author:

Nakajima Naoki1,Yoshizawa Akihiko1ORCID,Nakajima Tomoyuki2,Hirata Masahiro1,Furuhata Ayako1,Sumiyoshi Shinji1,Rokutan-Kurata Mariyo1,Sonobe Makoto3,Menju Toshi3,Miyamoto Ei3,Chen-Yoshikawa Toyofumi F3,Date Hiroshi3,Haga Hironori1

Affiliation:

1. Department of Diagnostic Pathology; Kyoto University Hospital; Kyoto Japan

2. Department of Laboratory Medicine; Shinshu University Hospital; Matsumoto Japan

3. Department of Thoracic Surgery; Kyoto University Hospital; Kyoto Japan

Publisher

Wiley

Subject

General Medicine,Histology,Pathology and Forensic Medicine

Reference44 articles.

1. GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut;Laverriere;J. Biol. Chem.,1994

2. GATA-6: a zinc finger transcription factor that is expressed in multiple cell lineages derived from lateral mesoderm;Morrisey;Dev. Biol.,1996

3. The transcription factor GATA6 is essential for branching morphogenesis and epithelial cell differentiation during fetal pulmonary development;Keijzer;Development,2001

4. GATA6 regulates differentiation of distal lung epithelium;Yang;Development,2002

5. Branching and differentiation defects in pulmonary epithelium with elevated Gata6 expression;Koutsourakis;Mech. Dev.,2001

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