Synthesis, Biological Evaluation, and Molecular Docking of (R)-2-((8-(3-aminopiperidin-1-yl)-3-methyl-7-(3-methylbut-2-en-1-yl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)methyl)benzonitrile as Dipeptidyl Peptidase IV Inhibitors-Reference-Cited by-同舟云学术

Synthesis, Biological Evaluation, and Molecular Docking of (R)-2-((8-(3-aminopiperidin-1-yl)-3-methyl-7-(3-methylbut-2-en-1-yl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)methyl)benzonitrile as Dipeptidyl Peptidase IV Inhibitors

Published:2015-11-23 Issue:2 Volume:87 Page:290-295
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Ran Yan¹,Pei Heying¹,Shao Mingfeng¹,Chen Lijuan¹

Affiliation:

1. State Key Laboratory of Biotherapy and Cancer Center; West China Hospital; Sichuan University; Keyuan Road 4, Gaopeng Street, High Technological Development Zone Chengdu 610041 China

Funder

National Key Programs of China

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12663/fullpdf

Reference16 articles.

1. Enhancing insulin action with physical activity to prevent and control diabetes;Colberg;ACSM'S Health Fitness,2008

2. DPP-4 inhibitors: what may be the clinical differentiators?;Gerich;Diabetes Res Clin Pract,2010

3. Established therapies for diabetes mellitus;Hsia;Curr Med Res Opin,2002