Synthesis of New Congeners of 1-methyl-3-aminoisoquinolines, Evaluation of Their Cytotoxic Activity,In SilicoandIn VitroStudy of Their Molecular Targets as PDE4B-Reference-Cited by-同舟云学术

Synthesis of New Congeners of 1-methyl-3-aminoisoquinolines, Evaluation of Their Cytotoxic Activity,In SilicoandIn VitroStudy of Their Molecular Targets as PDE4B

Published:2015-12-29 Issue:4 Volume:87 Page:575-582
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Lapa Gennady B.¹²,Tsunoda Toshiyuki³⁴,Shirasawa Senji³⁴,Baryshnikova Maria A.¹,Evseev Gregory G.¹,Afanasyeva Daria A.¹,Chigorina Elena A.⁵

Affiliation:

1. Blokhin Cancer Center; Kashirskoe sh 24 Moscow 115478 Russia

2. Pirogov Russian National Research Medical University (RNRMU); Ostrovitianov str. 1 Moscow 117997 Russia

3. Department of Cell Biology; Faculty of Medicine; Fukuoka University; Fukuoka 814-0180 Japan

4. Central Research Institute for Advanced Molecular Medicine; Fukuoka University; Fukuoka 814-0180 Japan

5. Federal State Unitary Enterprise IREA; Bogorodsky shaft, 3 Moscow 107076 Russia

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12691/fullpdf

Reference20 articles.

1. Objective assessment of cancer genes for drug discovery;Patel;Nat Rev Drug Discov,2013

2. The NCI60 human tumour cell line anticancer drug screen;Shoemaker;Nat Rev,2006

3. Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay;Alley;Cancer Res,1988

4. Computer aided prediction for medicinal chemistry via the Internet;Geronikaki;SAR QSAR Environ Res,2008

5. QSAR modelling of rat acute toxicity on the basis of PASS prediction;Lagunin;Mol Inform,2011

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1. PDE4 subtypes in cancer;Oncogene;2020-03-20

2. A facile metal-free one-pot synthesis of 3-aminoisoquinolines by intramolecular transannulation of 1-sulfonyl-4-(2-aminomethylphenyl)-1,2,3-triazoles;RSC Advances;2020