Role of anti-CD40 antibody-mediated costimulation blockade on non-Gal antibody production and heterotopic cardiac xenograft survival in a GTKO.hCD46Tg pig-to-baboon model-Reference-Cited by-同舟云学术

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Role of anti-CD40 antibody-mediated costimulation blockade on non-Gal antibody production and heterotopic cardiac xenograft survival in a GTKO.hCD46Tg pig-to-baboon model

Published:2013-10-29 Issue:1 Volume:21 Page:35-45
ISSN:0908-665X
Container-title:Xenotransplantation
language:en
Short-container-title:Xenotransplantation

Author:

Mohiuddin Muhammad M.¹,Singh Avneesh K.¹,Corcoran Philip C.¹,Hoyt Robert F.²,Thomas Marvin L.³,Lewis Billeta G. T.³,Eckhaus Michael³,Dabkowski Nicole L.⁴,Belli Aaron J.⁴,Reimann Keith A.⁴,Ayares David⁵,Horvath Keith A.¹

Affiliation:

1. Cardiothoracic Surgery Research Laboratory; NHLBI; NIH; Bethesda MD USA

2. Animal Program; NHLBI; NIH; Bethesda MD USA

3. Division of Veterinary Resources; ORS; NIH; Bethesda MD USA

4. MassBiologics; University of Massachusetts Medical School; Boston MA USA

5. Revivicor, Inc.; Blacksburg VA USA

Publisher

Wiley

Subject

Transplantation,Immunology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/xen.12066/fullpdf

Reference32 articles.

1. Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways;Larsen;Nature,1996

2. Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways;Cardona;Nat Med,2006

3. CD40-specific costimulation blockade enhances neonatal porcine islet survival in nonhuman primates;Thompson;Am J Transplant,2011

4. B-cell depletion extends the survival of GTKO.hCD46Tg pig heart xenografts in baboons for up to 8 months;Mohiuddin;Am J Transplant,2012

5. Potential of aspirin to inhibit thrombotic microangiopathy in alpha1,3-galactosyltransferase gene-knockout pig hearts after transplantation in baboons;Dor;Transplant Proc,2005

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3. Immunoprotection Strategies in β‐Cell Replacement Therapy: A Closer Look at Porcine Islet Xenotransplantation;Advanced Science;2024-06-17

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