3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration

Author:

Wang Hongbing1,Brown Paul C.2,Chow Edwin C.Y.3,Ewart Lorna4,Ferguson Stephen S.5,Fitzpatrick Suzanne6,Freedman Benjamin S.78,Guo Grace L.9,Hedrich William10,Heyward Scott11,Hickman James12,Isoherranen Nina13,Li Albert P.1415,Liu Qi3,Mumenthaler Shannon M.16,Polli James1,Proctor William R.17,Ribeiro Alexandre3,Wang Jian‐Ying18,Wange Ronald L.2,Huang Shiew‐Mei3

Affiliation:

1. Department of Pharmaceutical Sciences University of Maryland School of Pharmacy Baltimore Maryland USA

2. Center for Drug Evaluation and Research US Food and Drug Administration (FDA) Silver Spring Maryland USA

3. Office of Clinical Pharmacology Office of Translational Sciences Center for Drug Evaluation and Research US Food and Drug Administration (FDA) Silver Spring Maryland USA

4. Emulate Boston Massachusetts USA

5. Division of the National Toxicology Program National Institute of Environmental Health SciencesResearch Triangle Park North Carolina USA

6. Office of the Center Director Center for Food Safety and Applied Nutrition US Food and Drug Administration (FDA) Silver Spring Maryland USA

7. Division of Nephrology Department of Pathology Kidney Research Institute, and Institute for Stem Cell and Regenerative Medicine University of Washington Seattle Washington USA

8. Department of Medicine University of Washington Seattle Washington USA

9. Department of Pharmacology and Toxicology Ernest Mario School of Pharmacy Rutgers University Piscataway New Jersey USA

10. Pharmaceutical Candidate Optimization, Metabolism and Pharmacokinetics Bristol‐Myers Squibb Company Princeton New Jersey USA

11. BioIVT Halethorpe Maryland USA

12. NanoScience Technology Center University of Central Florida Orlando Florida USA

13. Department of Pharmaceutics School of Pharmacy University of Washington Seattle Washington USA

14. In Vitro ADMET Laboratories Columbia Maryland USA

15. In Vitro ADMET Laboratories Malden Massachusetts USA

16. Lawrence J. Ellison Institute for Transformative Medicine University of Southern California Los Angeles California USA

17. Predictive Toxicology, Safety Assessment Genentech, Inc South San Francisco California USA

18. Department of Surgery Cell Biology Group University of Maryland School of Medicine Baltimore Maryland USA

Funder

U.S. Food and Drug Administration

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3