Regulation of carboxylesterase-2 expression by p53 family proteins and enhanced anti-cancer activities among 5-fluorouracil, irinotecan and doxazolidine prodrug
Author:
Affiliation:
1. Department of Biomedical and Pharmaceutical Sciences; Center for Pharmacogenomics and Molecular Therapy; University of Rhode Island; Kingston; RI; USA
Publisher
Wiley
Subject
Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bph.12125/fullpdf
Reference47 articles.
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2. Preclinical efficacy of a carboxylesterase 2-activated prodrug of doxazolidine;Barthel;J Med Chem,2009
3. A pharmacokinetic-based test to prevent severe 5-fluorouracil toxicity;Bocci;Clin Pharmacol Ther,2006
4. Activation of v-Myb avian myeloblastosis viral oncogene homolog-like2 (MYBL2)-LIN9 complex contributes to human hepatocarcinogenesis and identifies a subset of hepatocellular carcinoma with mutant p53;Calvisi;Hepatology,2011
5. Transcriptional activation of the carboxylesterase 2 gene by the p53 pathway;Choi;Cancer Biol Ther,2006
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