Multicenter, randomized, controlled trial of S-1 monotherapy versus S-1 and interferon-α combination therapy for hepatocellular carcinoma with extrahepatic metastases

Author:

Nagano Hiroaki12,Obi Shuntaro3,Hatano Etsuro4,Kaneko Shuichi5,Kanai Fumihiko6,Omata Masao6,Tsuji Akihito7,Itamoto Toshiyuki8,Yamamoto Kazuhide9,Tanaka Masatoshi10,Kubo Shoji11,Hirata Koichi12,Nakamura Hideji13,Tomimaru Yoshito1,Yamanaka Takeharu14,Kojima Shinsuke15,Monden Morito1

Affiliation:

1. Department of Surgery, Graduate School of Medicine; Osaka University; Suita Japan

2. Department of Gastroenterological, Breast and Endocrine Surgery; Yamaguchi University Graduate School of Medicine; Ube Japan

3. Department of Gastroenterology and Hepatology; Kyoundo Hospital of the Sasaki Institute; Tokyo Japan

4. Department of Surgery, Graduate School of Medicine; Kyoto University; Kyoto Japan

5. Department of Gastroenterology; Kanazawa University Hospital; Kanazawa Japan

6. Department of Gastroenterology; University of Tokyo; Tokyo Japan

7. Department of Clinical Oncology; Kochi Health Science Center; Kochi Japan

8. Department of Surgery, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences; Hiroshima University; Hiroshima Japan

9. Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine; Dentistry and Pharmaceutical Sciences; Okayama Japan

10. Division of Gastroenterology, Department of Medicine; Kurume University School of Medicine; Kurume Japan

11. Department of Hepato-Biliary-Pancreatic Surgery; Osaka City University Graduate School of Medicine; Osaka Japan

12. Department of Surgery, Surgical Oncology & Science; Sapporo Medical University; Sapporo Japan

13. Division of Hepatobiliary and Pancreatic Disease, Department of Internal Medicine; Hyogo College of Medicine; Nishinomiya Japan

14. Department of Biostatistics; Yokohama City University School of Medicine; Yokohama Japan

15. Translational Research Informatics Center; Foundation for Biomedical Research and Innovation; Kobe Japan

Publisher

Wiley

Subject

Infectious Diseases,Hepatology

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