mTORC1 underlies age‐related muscle fiber damage and loss by inducing oxidative stress and catabolism-Reference-Cited by-同舟云学术

mTORC1 underlies age‐related muscle fiber damage and loss by inducing oxidative stress and catabolism

Published:2019-03-29 Issue:3 Volume:18 Page:e12943
ISSN:1474-9718
Container-title:Aging Cell
language:en
Short-container-title:Aging Cell

Author:

Tang Huibin¹²,Inoki Ken³⁴,Brooks Susan V.⁴,Okazawa Hideki⁵,Lee Myung¹²,Wang Junying³,Kim Michael¹²,Kennedy Catherine L.¹²,Macpherson Peter C. D.⁶,Ji Xuhuai⁷,Van Roekel Sabrina⁸,Fraga Danielle A.¹²,Wang Kun¹²,Zhu Jinguo¹²,Wang Yoyo¹²,Sharp Zelton D.⁹,Miller Richard A.⁸,Rando Thomas A.²¹⁰,Goldman Daniel⁶,Guan Kun‐Liang⁵,Shrager Joseph B.¹²

Affiliation:

1. Division of Thoracic Surgery, Department of Cardiothoracic Surgery Stanford University School of Medicine Stanford California

2. VA Palo Alto Healthcare System Palo Alto California

3. Life Science Institute University of Michigan Ann Arbor Michigan

4. Department of Molecular and Integrative Physiology University of Michigan Ann Arbor Michigan

5. Department of Pharmacology and Moores Cancer Center University of California San Diego La Jolla California

6. Molecular and Behavioral Neuroscience Institute and Department of Biological Chemistry University of Michigan Ann Arbor Michigan

7. Human Immune Monitoring Center, Stanford University School of Medicine Stanford California

8. Department of Pathology and Geriatrics Center University of Michigan Ann Arbor Michigan

9. Department of Molecular Medicine University of Texas Health Science Center at San Antonio San Antonio Texas

10. Paul F. Glenn Laboratories for the Biology of Aging and Department of Neurology and Neurological Sciences Stanford University School of Medicine Stanford California

Funder

National Institutes of Health

Publisher

Wiley

Subject

Cell Biology,Aging

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/acel.12943

Reference82 articles.

1. Sex‐ and tissue‐specific changes in mTOR signaling with age in C57 BL /6J mice

2. The Free Radical Theory of Aging Matures

3. Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy

4. Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy

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