Food‐dependent exercise‐induced anaphylaxis caused by leek and several allergens of the allium family

Author:

Takamatsu Noriko1ORCID,Nakamura Kazuko1,Suzuki Mao1,Ito Akiko1,Moriyama Tatsuya2,Kanbara Takeshi1

Affiliation:

1. Department of Dermatology Yokohama City University Medical Center Yokohama Japan

2. Department of Applied Bio. Chem. Factory of Agriculture Kindai University Osaka Japan

Abstract

AbstractExercise‐induced anaphylaxis (EIA) is a relatively rare condition but can be a diagnostic pitfall in daily practice. Leek allergy is extremely rare, and there have been no reports, to our knowledge, of leek‐dependent EIA. Here, we report the first case of exercise‐ and leek‐induced anaphylaxis. An 18‐year‐old woman presented with symptoms of anaphylaxis after exercise in the morning. Prick‐to‐prick tests for leek was 1+ and challenge test for heated leek was negative, but leek‐dependent physical exertion challenge test evoked anaphylaxis. We diagnosed food‐dependent EIA by some additional tests including immunoblotting assay with patient's serum. Leek allergy is an extremely rare condition, so careful interview and investigation of allergens is important to eliminate causative substances of anaphylaxis.

Publisher

Wiley

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