Phase 1 studies to assess the safety, tolerability and pharmacokinetics of JTE-052 (a novel Janus kinase inhibitor) ointment in Japanese healthy volunteers and patients with atopic dermatitis

Author:

Nakagawa Hidemi1,Nemoto Osamu2,Yamada Hiroyuki3ORCID,Nagata Takeshi3,Ninomiya Noriko3

Affiliation:

1. Department of Dermatology; The Jikei University School of Medicine; Tokyo Japan

2. Kojinkai Sapporo Skin Clinic; Hokkaido Japan

3. Clinical Development Department; Pharmaceutical Division; Japan Tobacco Inc.; Tokyo Japan

Funder

Japan Tobacco Inc.

Publisher

Wiley

Subject

Dermatology,General Medicine

Reference14 articles.

1. Atopic dermatitis;Bieber;N Engl J Med,2008

2. Clinical practice guidelines for the management of atopic dermatitis 2016;Saeki;J Dermatol,2016

3. The burden of atopic dermatitis: impact on the patient, family, and society;Carroll;Pediatr Dermatol,2005

4. Clinical guidance for treatment of patients with atopic dermatitis by tacrolimus ointment 0.1% and 0.03%;Japanese FK 506 Ointment Study Group;Jpn J Clin Dermatol,2003

5. JAK and STAT signaling molecules in immunoregulation and immunemediated disease;O'Shea;Immunity,2012

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