Design, synthesis, and evaluation of novel heteroaryldihydropyrimidine derivatives as non‐nucleoside hepatitis B virus inhibitors by exploring the solvent‐exposed region-Reference-Cited by-同舟云学术

Design, synthesis, and evaluation of novel heteroaryldihydropyrimidine derivatives as non‐nucleoside hepatitis B virus inhibitors by exploring the solvent‐exposed region

Published:2020-04-22 Issue:6 Volume:95 Page:567-583
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Yu Ji¹^ORCID,Jia Haiyong²,Guo Xiaowei³,Desta Samuel¹,Zhang Shuo¹,Zhang Jian¹,Ding Xiao¹,Liang Xiaohong³,Liu Xinyong¹^ORCID,Zhan Peng¹

Affiliation:

1. Department of Medicinal Chemistry Key Laboratory of Chemical Biology (Ministry of Education) School of Pharmaceutical Sciences Shandong University Jinan China

2. School of Pharmacy Weifang Medical University Weifang China

3. Department of Immunology Key Laboratory for Experimental, Teratology of Ministry of Education Shandong Provincial Key Laboratory of Infection and Immunology Shandong University School of Medicine Jinan China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cbdd.13512

Reference21 articles.

1. Nonaromatic Sulfonamide Group as an Ideal Anchor for Potent Human Carbonic Anhydrase Inhibitors: Role of Hydrogen-Bonding Networks in Ligand Binding and Drug Design

2. Small-Molecule Effectors of Hepatitis B Virus Capsid Assembly Give Insight into Virus Life Cycle

3. Current treatment of hepatitis B virus infections