Affiliation:
1. College of Textile Science and Engineering (International Institute of Silk) Key Laboratory of Intelligent Textile and Flexible Interconnection of Zhejiang Province Zhejiang Sci‐Tech University Hangzhou China
2. High Fashion Womenswear Institute Hangzhou Vocational and Technical College Hangzhou Zhejiang China
3. Department of Radiology The First Affiliated Hospital with Nanjing Medical University Nanjing China
4. Clothing Engineering Research Center of Zhejiang Province Zhejiang Sci‐Tech University Hangzhou China
5. College of Education Science Quanzhou Normal University Fujian China
Abstract
AbstractBackgroundA kind of prickle sensation, which is a composite feeling of pain and itch, can be evoked by mechanical stimulation of fiber ends from fabric surface against to human hairy skin, rather than glabrous skin. Now, a functional magnetic resonance imaging (fMRI) study was conducted to investigate the cognitive differences in the brain for mechanical prickling stimuli to the two types of skin.Materials and MethodsA nylon filament with the diameter of 205 μm and the length of 8 mm was used to deliver mechanical prickling stimuli respectively to two skin sites, fingertip (glabrous skin) and volar forearm (hairy skin), of eight healthy male subjects. Simultaneously, the technology of fMRI was adopted to acquire BOLD (Blood Oxygen Level‐Dependent) signals of brain functional response of the subjects.ResultsSomatosensory areas, emotional areas, and the posterior parietal cortex (especially the precuneus) are important brain regions that distinguish between the two conditions. The representation of mechanical prickling stimulation to glabrous skin in the brain favors much more the tactile information of the stimulation and contains no itch, while the key brain area, precuneus, involved in itch was activated by the same mechanical prickling stimulation to hairy skin, and brain response for the condition of hairy skin contains more emotional information, which plays an important role in pain processing.ConclusionTherefore, it can be inferred that a kind of stronger prickle sensation, which contains both pain and itch, was evoked by mechanical stimulation to hairy skin than glabrous skin.