Anti‐tumor effects of mAb against l ‐type amino acid transporter 1 ( LAT 1) bound to human and monkey LAT 1 with dual avidity modes

Author:

Ueda Shiho1,Hayashi Hidemi2,Miyamoto Takako1,Abe Shinya3,Hirai Kana1,Matsukura Kanji1,Yagi Hideki4,Hara Yuta1,Yoshida Kinji1,Okazaki Shogo5,Tamura Masakazu6,Abe Yuki7,Agatsuma Toshinori7,Niwa Shin‐ichiro2,Masuko Kazue1,Masuko Takashi1ORCID

Affiliation:

1. Cell Biology Laboratory School of Pharmacy Kindai University Osaka Japan

2. Link Genomics, Inc. Tokyo Japan

3. Laboratory of Biological Protection Institute for Viral Research, Kyoto University Kyoto Japan

4. School of Pharmacy International University of Health and Welfare Otawara Japan

5. Division of Development and Aging, Research Institute for Biomedical Sciences Tokyo University of Science Chiba Japan

6. Modality Research Laboratories, Biologics Division Daiichi Sankyo Co., Ltd Tokyo Japan

7. Biologics & Immuno‐Oncology Laboratories, R&D Division Daiichi Sankyo Co., Ltd Tokyo Japan

Funder

Japan Science and Technology Agency

Ministry of Education, Culture, Sports, Science and Technology

Publisher

Wiley

Subject

Cancer Research,Oncology,General Medicine

Reference53 articles.

1. Characterization of a monoclonal antibody (4F2) that binds to human monocytes and to a subset of activated lymphocytes;Haynes BF;J Immunol,1981

2. A proliferation‐associated rat cell surface antigen recognized by a murine monoclonal antibody;Hashimoto Y;Gan,1983

3. Monoclonal antibodies that inhibit activation and proliferation of lymphocytes. I. Expression of the antigen on monocytes and activated lymphocytes;Yagita H;J Immunol,1986

4. Cell surface glycoproteins involved in the stimulation of interleukin 1‐dependent interleukin 2 production by a subline of EL4 thymoma cells. II. Structure, biosynthesis, and maturation;Lüscher B;J Immunol,1985

5. Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family

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