Long-term treatment with romiplostim in patients with chronic immune thrombocytopenia: safety and efficacy

Author:

Kuter David J.1,Bussel James B.2,Newland Adrian3,Baker Ross I.4,Lyons Roger M.5,Wasser Jeffrey6,Viallard Jean-Francois7,Macik Gail8,Rummel Mathias9,Nie Kun10,Jun Susie10

Affiliation:

1. Massachusetts General Hospital; Boston; MA; USA

2. Division of Hematology; Departments of Pediatrics and Medicine; Weill Medical College of Cornell University; New York; NY; USA

3. Department of Haematology; The Royal London Hospital; Whitechapel; London; UK

4. Centre for Thrombosis and Haemophilia; Royal Perth Hospital; Murdoch University; Perth; WA; Australia

5. Cancer Care Centers South Texas/US Oncology; San Antonio; TX; USA

6. Division of Hematology-Oncology; Department of Medicine; University of Connecticut School of Medicine; Farmington; CT; USA

7. Université Victor Segalen Bordeaux 2; Hôpital Haut-Lévêque; CHU de Bordeaux; Pessac; France

8. University of Virginia; Charlottesville; VA; USA

9. Klinikum der Justus-Liebig-Universität; Giessen; Germany

10. Amgen Inc.; Thousand Oaks; CA; USA

Publisher

Wiley

Subject

Hematology

Reference32 articles.

1. Mechanisms of thrombocytopenia in chronic autoimmune thrombocytopenic purpura. Evidence of both impaired platelet production and increased platelet clearance;Ballem;Journal of Clinical Investigation,1987

2. Thrombocytopenia. I. Incidence and aetiology;Bottiger;Acta Medica Scandinavica,1972

3. Evaluation of bone marrow reticulin in patients with chronic immune thrombocytopenic purpura (ITP) treated with eltrombopag -data from the EXTEND study;Brynes;Blood (ASH Annual Meeting Abstracts),2011

4. A longitudinal prospective study evaluating the effects of eltrombopag treatment on bone marrow in patients with chronic immune thrombocytopenia: interim analysis at 1 year;Brynes;Blood (ASH Annual Meeting Abstracts),2012

5. AMG 531, a thrombopoiesis-stimulating protein, for chronic ITP;Bussel;New England Journal of Medicine,2006

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